Scientific Program

Friday, October 7, 2016

3:00pm 

Registration

5:00pm

Welcome from the University President: Hendrik Lehnert
Welcome the chair of the Symposium: Gabriela Riemekasten

5:20pm

Opening Lecture: Autoantibodies against GPCR – a new principle to understand diseases

6:00pmWelcome Reception
Saturday, October 8, 2016

9:00am

GPCRs and their modulation in neurological diseases
Madlen Löbel: Immunoadsorption to remove ß adrenergic and M acetylcholine receptor antibodies in Chronic Fatigue Syndrome
Lasse Melvaer Giil: Antibodies to signaling molecules and receptors in Alzheimer’s disease - Immune-related cognitive dysfunction and mortality.
Oral presentations from selected abstracts

10:00am

Coffee break

10:30am

GPCRs and their modulation in cardiovascular diseases
Florian Herse: AT1-Autoantibodies in hypertensive disease of pregnancy
Fritz Boege: Agonistic autoantibodies against 1-adrenergic receptors in dilated cardiomyopathy
Annekathrin Haberland: BC 007, an aptamer for the neutralization of functional autoantibodies directed against GPCR that are identified by a functional test
Oral presentations from selected abstracts

12:00pm

Lunch

1:15pm

Poster Session

2:00pm

GPCRs and their modulation in hemato-oncological diseases
Thomas Luft: Role of autoantibodies directed against GPCRs in GVHD after allogenic SCT
Frank Gieseler: PAR2, a G-protein coupled receptor protein (GPR11): Possible relevance of aberrant expression by tumor cells
Oral presentations from selected abstracts

3:00pm

Coffee Break

3:30pm

GPCRs and their modulation in rheumatic diseases
Gabriela Riemekasten: Antibodies against GPCR in systemic sclerosis
Xinhua Yu: Autoantibodies against peptides of GPCRs in primary Sjögren’s syndrome
Otávio Cabral-Marques: Physiological IgG autoantibodies regulate a network of G protein coupled receptors and growth factors
Oral presentations from selected abstracts

6:00pm

Social event

8:00pm

Dinner at the “Kartoffelkeller” in the historical center of Lübeck

Sunday, October 9, 2016

9:00am

GPCR antibodies and their signaling
Duska Dragun: Personalized medicine for transplant recipients according to anti-GPCR antibody status
Aurélie Philippe: New approaches to study functional selectivity in GPCR signaling
Christian Sadik: SSc- IgG effects are mediated through distinct pathways in THP-1 cells
Oral presentations from selected abstracts

10:30am

Coffee break

11:00pm

Therapeutic approaches regarding GPCR modulation
Roland Jahns: Novel therapeutic approaches in cardiac autoimmunity:
Blocking peptides against beta1-adrenoceptor autoantibodies
Manuela Camino: Autoantibodies against beta 1 adrenergic receptors in dilated cardiomiopathy in children - treatment with immunoadsorption
Oral presentations from selected abstracts

12:00pm

Panel discussion and closing remarks: Gabriela Riemekasten Future directions and therapeutic approaches

12:45pm

Lunch