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      • GPCR-Symposium 2020
        • Program
      • GPCR-Symposium 2018
      • GPCR-Symposium 2016
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Program

The program of the International RAB symposium on regulatory autoantibodies targeting G-protein-coupled receptors will address the field of GPCR antibody research with specific highlights on:

  • anti-GPCR antibodies as biomarker in disease and therapeutic response
  • anti-GPCR antibody-mediated pathways
  • regulation of anti-GPCR abs
  • Identification of novel therapeutic targets
Why to join?

Our aim is to bring scientists together, initiate discussions and stimulate research on these challenges. We would like to strengthen the research network to:

  • identify new pathogenic targets, biomarkers and signalling pathways to find a holistic way to understand diseases
  • To identify effectors that influence the disease-specific transcriptome and secretome
  • understand how environmental factors and genes can be transformed into molecular pathways
  • Develop novel therapeutic strategies

Thursday, 15.09.2022

TimeTitle
Provocative statements
09:00All diseases are autoimmune diseases
Y. Shoenfeld
09:30All diseases are GPCR abs mediated diseases
G. Riemekasten
10:00Coffee break
COVID-19 and natural regulatory abs
10:30Anti-GPCR and acute COVID infection
F.Tran
11:00COVID-Vaccination and anti-GPCR abs
T. Lange
11:30Role of GPCR abs in Post-COVID syndrome
C. Scheibenbogen
12:00Lunch break
13:45Poster Session
Progress in preclinical models to measure RAB ab effects
14:30Animal models
X. Yu
15:00Modification of animal models and GPCR/monoclonal abs
F. Petersen
15:30Stroke and anti-GPCR abs
M. Endres
16:00Coffee break
Anti-GPCR binding biology
16:30Glycocalix and their interplay with GPCR abs
K. Kusche-Viehrog
17:00Ab binding by measuring the crystal structures of GPCRs
P. Scherer
17:30Biology of regulatory abs, insight from bioinformatics
O. Cabral Marques
18:30Get together, Networking in the industrial exhibition
 

Friday, 15.09.2022

TimeTitle
Natural RAB-induced  signalling
09:00What comes after ab binding? How to go beyond the cell surface?
E. Kostenis
09:30Signalling of GPCR abs in different cellular models
R. Catar
10:00Ab-induced proteome
H. Grasshoff
10:30Coffee break
Therapy
11:30Aptamer BQ007, a novel therapeutic agent?
B. Hohenberger
12:00Interacting with GPCR by peptides
J. Bernhagen
12:30Lunch and Postersession
Fibromyalgia and ME/CSF as another challenge
14:00Fibromyalgia: ab-mediated pathogenesis
C. I. Svensson
14:30GPCR abs and confounding factors: Learning from fibromyalgia
F. Lübbers
15:00Role of GPCR abs in chronic fatigue syndrome
F. Sotzny
15:30Coffee break
New pathogenesis insights from SSc
16:00GPCR abs in systemic sclerosis
S. Schinke
16:30Measuring GPCR ab characteristics
A. Kehrstein-Stehle
17:00GPCR abs and EVs as the bad boys affecting immune cell functions
A. Hackel
Lecture
17:30EVs and antibody-interactions
D. Pisetzky
What are the next steps, how to proceed?
18:15General discussion
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