Scientific Program

 

 

Friday, 28. September 2018
4:30 pmRegistration
5:45 pm

Welcome and opening lectures

Welcome note by the Symposium´s Chair
Gabriela Riemekasten

Welcome note by the University President
Gabriele Gillesen-Kaesbach

The Mosaik and Kaleidoskope of Autoimmunity
Yehuda Shoenfeld

Network-based analysis reveals signatures of IgG autoantibodies targeting G protein-coupled receptors in health and disease
Gabriela Riemekasten

7:00 pmGet-together

 

 

Saturday, 29. September 2018
9:00am 

Anti-GPCR ab: advantages, pitfalls and problem in the diagnosis

Functional ab causing psychiatric manifestations: Lessons need to be learned
Yehuda Shoenfeld

Lessons From Anti-TSH-Receptor Autoantibodies: Challenges And Pitfalls In Diagnostics
Simon Lytton 

Patterns of 31 new autoantibodies against G protein-coupled receptors and growth factors
Susanne Schinke

Talks from selected abstracts

10:30am  Coffee and Industrial Exhibition
11:00am  

Are anti-GPCR ab pathogenic?

Diagnostics of beta-adrenergic receptor autoantibodies in chronic heart failure
Fritz Boege

Novel targets in the diagnosis of autoimmune and non-autoimmune diseases
Harald Heidecke

Anti-AT1R ab and autoimmunity to GPCR as cause or contributor to skin fibrosis and interstitial lung disease
Xinhua Yu

Monoclonal anti-AT1R ab from a SSc mouse model: evaluation of their functions
Frank Petersen

Transfer of PBMC from SSc patients to immunodeficient mice leads to the production of autoantibodies against AT1R and ETAR
Xiaoyang Yue

Talks from selected abstracts

12:30pm  Lunch and Industrial Exhibition
1:30pm 

Poster Session

Transfer of PBMC from SSc patients to immunodeficient mice leads to the production of autoantibodies against AT1R and ETAR (P01)
Xiaoyang Yuea

ß1-adrenergic receptor autoantibody levels are higher in patients with Graves’ hyperthyroidism than in matched healthy controls and decrease after anti-thyroid treatment (P02)
Anna Lundgren

Sialylated autoantigen-reactive IgG antibodies attenuate disease development in mouse models of lupus nephritis and rheumatoid arthritis (P03)
Marc Ehlers

Autoantibodies targeting G-protein coupled receptors in RA and SLE (P04)
Xinhua Yu

Identification and characterization of cytomegalovirus-specific CD8+ T cells in systemic sclerosis (P05)
Gesa Balsen

Autoantibodies targeting complement receptors 3a and 5a are decreased in ANCA-associated vasculitis (P06)
Sebastian Klapa

Impact of regulatory (auto-)antibodies against G-protein-coupled receptors on blood pressure in women ten years after early-onset preeclampsia (P07)
Anna Birukov

Organotropism of anti-CXCR3/4- and anti-ETAR/-AT1R-mediated leukocyte migration in inflammatory and autoimmune disease (P08)
Laurence Johanson

Autoantibodies targeting muscarinic acetylcholine receptors: implications on fatigue in systemic sclerosis (P09)
Sabine Sommerlatte

Role of anti-alpha-adrenoceptor autoantibodies and leukocytic alpha-adrenoceptors in primary Raynaud’s phenomenon (P10)
Catharina Frahm

Autoantibodies in serum of systemic scleroderma patients: peptide-based epitope mapping indicates increased binding to cytoplasmic domains of CXCR3 (P11)
Ann-Katrin Regensburger

Detection and functional characterization of angiotensin receptor Type 1 autoantibodies: establishment and clinical translation (P12)
Valérie Boivin-Jahns

Inflamed tissue contributes to the emergence of auto-reactivity in granulomatosis with polyangiitis (P13)
Gesche Weppner

Patterns of 31 new autoantibodies against G protein-coupled receptors and growth factors (P14)
Susanne Schinke

New insights into the diagnostics of autoantibodies against G-protein receptors – pitfalls in the autoantibody detection (P15)
Annekathrin Haberland

Network-based analysis reveals signatures of IgG autoantibodies targeting G protein-coupled receptors in healthy and diseases (P16)
Gabriela Riemekasten

2:30pm  

Signaling of anti-GPCR ab: can we identify novel targets?

Signaling and GPCR biology using cell models
Aurelie Philippe

Lessons from dermatology: Anti-Dsg1/3 und anti-BP180-induced signaling
Ralf Ludwig

Role of antibodies against PAR-1 and PAR-2 in cancer in the kidney transplant recipients
Rusan Catar

Sialylated autoantigen-reactive IgG antibodies attenuate disease development in mouse models of lupus nephritis and rheumatoid arthritis
Marc Ehlers

Autoantibodies targeting complement receptors 3a and 5a are decreased in ANCA-associated vasculitis
Sebastian Klapa

Impact of regulatory (auto-)antibodies against G-protein-coupled receptors on blood pressure in women ten years after early-onset preeclampsia
Ralf Dechend

Talks from selected abstracts

4:00pmCoffee and Industrial Exhibition
4:30pm

Anti-GPCR ab as marker for diseases and therapeutic responses 

Antibodies against complement receptors: impact in pathophysiology?
Christian Karsten

Anti-GPCR ab in atherosclerosis
Zouhair Aherrahrou

Immunoadsorption in Vascular Dementia - a novel approach to Alzheimer´s Disease?
Hans Grabe

First results of the prospective ETiCS: inflammation rather than ischemia triggers the development of cardiac GPCR-autoantibodies
Roland Jahns

Talks from selected abstracts

6:30pmSocial Event with Dinner
Classic concert by participants
Restaurant Miera

 

 

Sunday, 30. September 2018
9:00am

How to target effects of functional antibodies

Chronic Fatigue-Syndrom and Apherese
Carmen Scheibenbogen

The aptamer BC 007 completely neutralizes agonistic autoantibodies directed against ß1-adrenoceptors: Results of a phase 1 trial
Niels-Peter Becker

Agonistic antibody disesaes = Autoimmune diseases ? - From bench to bedside
Rudolf Kunze

Detection and functional characterization of angiotensin receptor Type 1 autoantibodies: establishment and clinical translation
Valérie Boivin-Jahns

Talks from selected abstracts

10:20amCoffee and Industrial Exhibition
10:50pm

Summary and Closing Remarks

Challenges in the research of anti-GPCR ab
Duska Dragun

Closing Remarks